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Christopher Lee (Dr. Fu Manchu), Tsai Chin (Lin Tang) and Howard Marion-Crawford (Dr. Petrie) are the only actors to appear in all five "Fu Manchu" films.
Douglas Wilmer replaced Nigel Green.
The video release of this film includes a clip of the climax from "The Face of Fu Manchu (1965)." This caused some initial confusion as some viewers thought Nigel Green was going to reprise his role of Nayland Smith.
Rupert Davies and Roger Hanin receive 'Guest Stars' credits.
Nigel Green declined the opportunity to reprise his role of Nayland Smith.
"Fu Manchu: As you were the leader of the rebellion, you shall be the first to go to the snakes."
"Lin Tang: [hears gunfire] More shooting. The temple must be full of soldiers. Fu Manchu: It is of no importance. Within a few moments the entire world will capitulate to me. This is the destiny of Fu Manchu."